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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. ACTN4, actinin, alpha 4
Sequence ID:NM_004924
RefSeqGene ID:NG_007082
Entrez Gene ID:81
Ensembl ID:ENSG00000130402

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 39138326 - 39216500

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3842046Full LengthBC005033actinin, alpha 4
4843317IncompleteBC015620actinin, alpha 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004915  

Protein Infomation

NM_004924 NP_004915 O43707 efhand

Related Sequences

U48734 AAC17470 O43707
BC005033 AAH05033 O43707
BC015620 AAH15620 Q96BG6
DQ431186 ABD96103 A4K467
DQ893439 ABM84365  
DQ896777 ABM87776  
GU987085 ADG03678 D6PXK4
D89980 BAA24447 O43707
AK299955 BAG61782 B4DSX0
AK304554 BAG65349 B4E337

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ACTN4 NP_004915 M.musculus Actn4 60595 Gene Info NP_068695 99
R.norvegicus Actn4 63836   NP_113863 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)