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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ACSL4, acyl-CoA synthetase long-chain family member 4
Sequence ID:NM_004458
NM_022977
RefSeqGene ID:NG_008053
Entrez Gene ID:2182
Ensembl ID:ENSG00000068366

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MENTAL RETARDATION, X-LINKED 63 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq22.3-q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 108884565 - 108976512

 Exon Info From UCSC:
NM_004458
NM_022977

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4824121Full LengthBC034959acyl-CoA synthetase long-chain family member 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004449  NP_075266  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004458 NP_004449     AMP-binding
NM_022977 NP_075266 O60488 EC 6.2.1.3 AMP-binding

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF030555 AAC17493 O60488 EC 6.2.1.3
BC034959 AAH34959 O60488 EC 6.2.1.3
DQ890835 ABM81761    
DQ893990 ABM84916    
AB061713 BAB86900 Q8TAF6  
AB061714 BAB86901 Q8TAF6  
AK292070 BAF84759 Q5JWV8  
AK294915 BAG58000 B4DH39  
Y12777 CAA73314 O60488 EC 6.2.1.3
Y13058 CAA73501 O60488 EC 6.2.1.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ACSL4 NP_075266 M.musculus Acsl4 50790 Gene Info NP_997508 97
R.norvegicus Acsl4 113976   NP_446075 97
A.thaliana LACS9 844094   NP_177882 47
C.elegans acs-16 176005   NP_498568 47
C.elegans acs-17 180859   NP_508993 46
S.cerevisiae FAA4 855288   NP_013974 35
S.cerevisiae FAA3 854808   NP_012257 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)