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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. VAV3, vav 3 guanine nucleotide exchange factor
Sequence ID:NM_001079874
NM_006113
Entrez Gene ID:10451
Ensembl ID:ENSG00000134215

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 108145723 - 108231126

 Exon Info From UCSC:
NM_001079874
NM_006113

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9052487Full LengthBC143969vav 3 guanine nucleotide exchange factor
100062223Full LengthBC156726vav 3 guanine nucleotide exchange factor
100015251BC146365vav 3 guanine nucleotide exchange factor

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006104  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001079874 NP_001073343    
NM_006113 NP_006104 Q9UKW4 SH2
SH3_1
C1_1
PH
CH
RhoGEF
SH3_2

Related Sequences

 
mRNAGenPeptSwissProt
AF067817 AAC79695 Q9UKW4
AF035442 AAD03799 Q9UKW4
AF118886 AAD20348 Q9UKW4
AF118887 AAD20349 Q9UKW4
BC143969 AAI43970 Q9UKW4
BC146365 AAI46366  
BC156726 AAI56727  
AK295166 BAG58178 B4DHL6
AK300474 BAG62191 B4DU29
AK304088 BAG64994 Q9UKW4
AK296537 BAH12381 B7Z3Z5
AK316295 BAH14666 Q9UKW4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens VAV3 NP_006104 M.musculus Vav3 57257 Gene Info NP_065251 95
R.norvegicus Vav3 295378   XP_227600 95
C.elegans vav-1 181153   NP_001041223 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)