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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FGFR1, fibroblast growth factor receptor 1
Sequence ID:NM_001174063
NM_001174064
NM_001174065
NM_001174066
NM_001174067
NM_015850
NM_023105
NM_023106
NM_023110
NM_023107
NM_023108
NM_023109
NM_023111
NM_032191
RefSeqGene ID:NG_007729
Entrez Gene ID:2260
Ensembl ID:ENSG00000077782

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
ANTLEY-BIXLER SYNDROME WITHOUT GENITAL ANOMALIES OR DISORDERED STEROIDOGENESISFGFR2
HYPOGONADOTROPIC HYPOGONADISM 2 WITH OR WITHOUT ANOSMIA 
HYPOGONADOTROPIC HYPOGONADISM 7 WITH OR WITHOUT ANOSMIACHD7
CHD7
FGF8
GNRH1
GNRHR
KISS1
KISS1R
NELF
PROK2
TAC3
TACR3
JACKSON-WEISS SYNDROMEFGFR2
OSTEOGLOPHONIC DYSPLASIA 
PFEIFFER SYNDROMEFGFR2
TRIGONOCEPHALY 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 38270248 - 38326139

 Exon Info From UCSC:
NM_001174063
NM_001174064
NM_001174065
NM_001174066
NM_001174067
NM_015850
NM_023105
NM_023106
NM_023110
NM_023107
NM_023108

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3896359Full LengthBC018128fibroblast growth factor receptor 1
3911101Full LengthBC015035fibroblast growth factor receptor 1
30387634Full LengthBC091494fibroblast growth factor receptor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_075598  NP_056934  NP_075594  NP_075593  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001174063 NP_001167534      
NM_001174064 NP_001167535      
NM_001174065 NP_001167536      
NM_001174066 NP_001167537      
NM_001174067 NP_001167538      
NM_015850 NP_056934     ig
Pkinase
I-set
V-set
Pkinase_Tyr
NM_023105 NP_075593     ig
Pkinase
I-set
V-set
Pkinase_Tyr
NM_023106 NP_075594     ig
I-set
Pkinase_Tyr
NM_023110 NP_075598 P11362 EC 2.7.10.1 ig
I-set

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M34641 AAA35835 P11362 EC 2.7.10.1
M34185 AAA35836 P11362 EC 2.7.10.1
M34186 AAA35837 P11362 EC 2.7.10.1
M34187 AAA35838 P11362 EC 2.7.10.1
M34188 AAA35839 P11362 EC 2.7.10.1
M60485 AAA35840 P11362 EC 2.7.10.1
M63887 AAA35958 P11362 EC 2.7.10.1
M63888 AAA35959 P11362 EC 2.7.10.1
M63889 AAA35960 P11362 EC 2.7.10.1
M37722 AAA75007 P11362 EC 2.7.10.1
S76658 AAD14230 A0N6Y5  
BC015035 AAH15035 P11362 EC 2.7.10.1
BC018128 AAH18128 P11362 EC 2.7.10.1
BC091494 AAH91494 P11362 EC 2.7.10.1
AF173898 AAQ13645 Q7Z2S2  
DQ894999 ABM85925    
EU826596 ACF47632 B5A958  
EU826597 ACF47633 B5A959  
FJ809916 ACO38645 C1KBH7  
FJ809917 ACO38646 P11362 EC 2.7.10.1
AB208919 BAD92156 P11362 EC 2.7.10.1
AK222718 BAD96438 P11362 EC 2.7.10.1
AK223126 BAD96846 Q53G05  
AK291754 BAF84443 P11362 EC 2.7.10.1
AK292470 BAF85159 P11362 EC 2.7.10.1
X51803 CAA36101 P11362 EC 2.7.10.1
X52833 CAA37015 P11362 EC 2.7.10.1
X57118 CAA40400 P11362 EC 2.7.10.1
X57119 CAA40401 P11362 EC 2.7.10.1
X57120 CAA40402 P11362 EC 2.7.10.1
X57121 CAA40403 P11362 EC 2.7.10.1
X57122 CAA40404 P11362 EC 2.7.10.1
X66945 CAA47375 P11362 EC 2.7.10.1
Y00665 CAA68679 P11362 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FGFR1 NP_001167538 M.musculus Fgfr1 14182 Gene Info NP_034336 99
R.norvegicus Fgfr1 79114   NP_077060 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)