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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MLL, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
Sequence ID:NM_001197104
NM_005933
NM_024891
RefSeqGene ID:NG_027813
Entrez Gene ID:4297
Ensembl ID:ENSG00000118058

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
WIEDEMANN-STEINER SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 118344306 - 118394632


Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001009939 NP_001009939     Septin
NM_001197104 NP_001184033      
NM_002688 NP_002679 Q99719   Septin
NM_005933 NP_005924 Q03164 EC 2.1.1.43  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L04284 AAA58669 Q03164 EC 2.1.1.43
L01986 AAA92511 Q03164 EC 2.1.1.43
S66432 AAB28545 Q03164 EC 2.1.1.43
S78570 AAB34770 Q03164 EC 2.1.1.43
S78571 AAB34771 Q9UM91  
U74628 AAB93438 Q99719  
AF061154 AAC25958    
U85431 AAD00564 O95648  
AF232000 AAG26334 Q9HBJ4  
AF232001 AAG26335 Q9HBJ3  
AF272370 AAG31978 Q9HB88  
AF272371 AAG31979 Q9HB87  
AF272378 AAG31983 Q9HB83  
AF272380 AAG31984 Q9HB82  
AF272381 AAG31985 Q9HB81  
AF272382 AAG31986 Q9HB80  
BC025261 AAH25261 Q99719  
AF487906 AAM14566 Q8TD97  
AF512944 AAM82546 Q8NFI1  
AY187942 AAO38742 Q86YP1  
AY187943 AAO38743 Q86YP0  
AY187944 AAO38744 Q86YN9  
AY187945 AAO38745 Q86YN8  
D14540 BAA03407 Q03164 EC 2.1.1.43
AK056273 BAB71133 Q99719  
AB209508 BAD92745 Q03164 EC 2.1.1.43
AK295635 BAG58509 B4DIJ7  
AK295940 BAG58724 B4DJ62  
AK303179 BAG64274 B4E012  
Y11593 CAA72332 Q99719  
CR456545 CAG30431 Q99719  
CU013145 CAK54576    
CU013433 CAK54875    
FM165198 CAQ60122 B3W6H7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MLL NP_005924 M.musculus Mll1 214162 Gene Info NP_001074518 91
R.norvegicus Mll1 315606   NP_001101609 91

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)