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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PDK2, pyruvate dehydrogenase kinase, isozyme 2
Sequence ID:NM_001199898
Entrez Gene ID:5164
Ensembl ID:ENSG00000005882

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21.33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 48172100 - 48188422

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3831465Full LengthBC005811pyruvate dehydrogenase kinase, isozyme 2
4272593Full LengthBC063137pyruvate dehydrogenase kinase, isozyme 2
4690182Full LengthBC040478pyruvate dehydrogenase kinase, isozyme 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002602  

Protein Infomation

NM_001199898 NP_001186827      
NM_001199899 NP_001186828      
NM_001199900 NP_001186829      
NM_002611 NP_002602 Q15119 EC HATPase_c

Related Sequences

L42451 AAC42010 Q15119 EC
BC005811 AAH05811 Q15119 EC
BC040478 AAH40478 Q15119 EC
BC063137 AAH63137 Q15119 EC
JF432702 ADZ15919    
AK290522 BAF83211 Q15119 EC
AK055119 BAG51472 Q15119 EC
AK293600 BAG57064 B4DEF3  
AK297089 BAG59604 B4DLP2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PDK2 NP_002602 R.norvegicus Pdk2 81530   NP_110499 98
M.musculus Pdk2 18604 Gene Info NP_598428 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta