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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. L2HGDH, L-2-hydroxyglutarate dehydrogenase
Sequence ID:NM_024884
RefSeqGene ID:NG_008092
Entrez Gene ID:79944
Ensembl ID:ENSG00000087299

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
L-2-HYDROXYGLUTARIC ACIDURIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 50713182 - 50778947

NM_024884 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1948365070915350713970
483749685073207550732206
496951265073447050734627
512752945073588050736047
529553295074523750745271
533054925075058850750750
549356245076083250760963
562557765076873450768885
577758925076961950769734
589361115077872850778946

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3504996Full LengthBC006117L-2-hydroxyglutarate dehydrogenase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_079160  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_024884 NP_079160 Q9H9P8 EC 1.1.99.2 DAO

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC006117 AAH06117 Q9H9P8 EC 1.1.99.2
AY757363 AAV52330 Q9H9P8 EC 1.1.99.2
JF432174 ADZ15391    
AK022680 BAB14174 Q9H9P8 EC 1.1.99.2
AK292627 BAF85316 A8K9B2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens L2HGDH NP_079160 M.musculus L2hgdh 217666 Gene Info NP_663418 83
R.norvegicus L2hgdh 314196   NP_001101498 81
A.gambiae AgaP_AGAP007868 1278087   XP_317624 57
D.melanogaster CG10639 35156   NP_609923 57
C.elegans Y45G12B.3 178733   NP_503730 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)