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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GUSB, Glucuronidase, beta
Sequence ID:NM_000181
RefSeqGene ID:NG_016197
Entrez Gene ID:2990
Ensembl ID:ENSG00000169919

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MUCOPOLYSACCHARIDOSIS VII 

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q21.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 65425674 - 65441147

 Exon Info From UCSC:
NM_000181

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4662011Full LengthBC014142glucuronidase, beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000172  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000181 NP_000172 P08236 EC 3.2.1.31 Glyco_hydro_2
Glyco_hydro_2_C
Glyco_hydro_2_N

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M15182 AAA52561 P08236 EC 3.2.1.31
M10618 AAA52621 P08236 EC 3.2.1.31
BC014142 AAH14142 P08236 EC 3.2.1.31
DQ892941 ABM83867    
DQ896190 ABM87189    
AK223406 BAD97126 P08236 EC 3.2.1.31
AK312752 BAG35619 B2R6X2  
AK300223 BAG61991 B4DTH9  
AK303819 BAG64768 B4E1F6  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GUSB NP_000172 R.norvegicus Gusb 24434   NP_058711 76
M.musculus Gusb 110006 Gene Info NP_034498 75
D.melanogaster CG15117 37197   NP_611395 49
A.gambiae AgaP_AGAP011859 1280794   XP_320660 49
C.elegans Y105E8B.9 173326   NP_493548 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)