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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PFKL, Phosphofructokinase, liver
Sequence ID:NM_002626
Entrez Gene ID:5211
Ensembl ID:ENSG00000141959

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 45719978 - 45747237

 Exon Info From UCSC:
NM_002626

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3009907Full LengthBC009919phosphofructokinase, liver
3029577Full LengthBC008964phosphofructokinase, liver
3347301Full LengthBC007536phosphofructokinase, liver
4040291Full LengthBC006422phosphofructokinase, liver
3458877IncompleteBC018295phosphofructokinase, liver
3545993IncompleteBC004920phosphofructokinase, liver

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002617  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002626 NP_002617 P17858 EC 2.7.1.11 PFK

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC004920 AAH04920 Q9BSP4  
BC006422 AAH06422 P17858 EC 2.7.1.11
BC007536 AAH07536 P17858 EC 2.7.1.11
BC008964 AAH08964 P17858 EC 2.7.1.11
BC009919 AAH09919 P17858 EC 2.7.1.11
BC018295 AAH18295 Q7L2M7  
DQ893435 ABM84361    
DQ896792 ABM87791    
AB209127 BAD92364 Q59GI2  
AK054735 BAG51419 B3KNQ7  
AK303605 BAG64620 B4E108  
X15573 CAA33597 P17858 EC 2.7.1.11
BX537446 CAD97688 Q7Z3R9  
BX641051 CAE46026 Q6MZK4  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PFKL NP_002617 M.musculus Pfkl 18641 Gene Info NP_032852 94
R.norvegicus Pfkl 25741   NP_037322 94
S.pombe pfk1 2539972   NP_595946 48
N.crassa NCU00629 3881966   XP_965769 48
S.cerevisiae PFK2 855245   NP_013932 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta