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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PAPOLA, poly(A) polymerase alpha
Sequence ID:NM_001252006
NM_001252007
NM_032632
RefSeqGene ID:NG_030439
Entrez Gene ID:10914
Ensembl ID:ENSG00000090060

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q32.31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 97033047 - 97033448


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5271668Full LengthBC036014poly(A) polymerase alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_116021  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001252006 NP_001238935      
NM_001252007 NP_001238936      
NM_032632 NP_116021 P51003 EC 2.7.7.19 NTP_transf_2
PAP_RNA-bind
PAP_central

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC000927 AAH00927 P51003 EC 2.7.7.19
BC036014 AAH36014 P51003 EC 2.7.7.19
AK295020 BAG58079 B4DHB8  
AK302406 BAG63716 B4DYF4  
AK302984 BAG64124 B4DZL2  
AK303402 BAG64456 B4DZL2  
AK316168 BAH14539 B7ZA53  
BX161482 CAD61935 P51003 EC 2.7.7.19
BX248301 CAD62628 P51003 EC 2.7.7.19
BX248753 CAD66560 P51003 EC 2.7.7.19

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PAPOLA NP_116021 M.musculus Papola 18789 Gene Info NP_035242 96
R.norvegicus Papola 314417   NP_001101526 96
C.elegans F43G6.5 174816   NP_496524 51
C.elegans T15H9.6 174513   NP_496067 50
S.pombe pla1 2541099   NP_595362 47
C.elegans pap-1 179458   NP_505683 47
S.cerevisiae PAP1 853871   NP_012927 47
A.thaliana PAPS2 817127   NP_001031417 46
N.crassa NCU08983 3875168   XP_959011 44
A.thaliana nPAP 829421   NP_195011 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta