Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CTSZ, cathepsin Z
Sequence ID:NM_001336
RefSeqGene ID:NG_023300
Entrez Gene ID:1522
Ensembl ID:ENSG00000101160

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MYCOBACTERIUM TUBERCULOSISCCL2
CD209
CISH
IFNG
IFNGR1
IRGM
IRGM
MC3R
SLC11A1
SP110
TIRAP

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q13.32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 57570242 - 57582153

NM_001336 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
185905757024157570813
5917535757169357571855
7549045757265757572807
90510845757651957576698
108512485758137657581539
124915175758204057582308

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5018854Full LengthBC042168cathepsin Z

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001327  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001336 NP_001327 Q9UBR2 EC 3.4.18.1 Peptidase_C1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF073890 AAC61477 Q9UBR2 EC 3.4.18.1
AF009923 AAC63141 Q9UBR2 EC 3.4.18.1
AF136273 AAF13145 Q9UBR2 EC 3.4.18.1
BC042168 AAH42168 Q9UBR2 EC 3.4.18.1
BT019915 AAV38718 Q5U000  
AK314931 BAG37437 Q9UBR2 EC 3.4.18.1
AM392668 CAL37546    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CTSZ NP_001327 M.musculus Ctsz 64138 Gene Info NP_071720 85
C.elegans cpz-1 171829   NP_491023 64

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)