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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PSMC3, proteasome (prosome, macropain) 26S subunit, ATPase, 3
Sequence ID:NM_002804
Entrez Gene ID:5702
Ensembl ID:ENSG00000165916

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 47440325 - 47447786

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822002Full LengthBC008713proteasome (prosome, macropain) 26S subunit, ATPase, 3
6195828Full LengthBC073165proteasome (prosome, macropain) 26S subunit, ATPase, 3
40032717Full LengthBC106920proteasome (prosome, macropain) 26S subunit, ATPase, 3
4611035IncompleteBC107804proteasome (prosome, macropain) 26S subunit, ATPase, 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002795  

Protein Infomation

NM_002804 NP_002795 P17980 AAA

Related Sequences

M34079 AAA36666 P17980
BC008713 AAH08713 P17980
BC073165 AAH73165 P17980
BC106920 AAI06921 P17980
BC107804 AAI07805 P17980
DQ892981 ABM83907  
DQ896229 ABM87228  
AK222485 BAD96205 P17980
AK291896 BAF84585 A8K781
AK313518 BAG36298 P17980
CR456731 CAG33012 P17980

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PSMC3 NP_002795 R.norvegicus Psmc3 29677   NP_113783 99
M.musculus Psmc3 19182 Gene Info NP_032974 99
A.gambiae AgaP_AGAP000616 1271616   XP_310465 86
D.melanogaster Tbp-1 42805   NP_524464 85
C.elegans rpt-5 172238   NP_491672 83
A.thaliana RPT5B 837431   NP_172384 78
A.thaliana RPT5A 819718   NP_187204 77
N.crassa NCU04414 3873668   XP_957491 75
P.falciparum PF11_0314 810861   XP_001347985 74
S.pombe rpt5 3361462   NP_001018261 72
S.cerevisiae RPT5 854284   NP_014760 70

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)