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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF4E, eukaryotic translation initiation factor 4E
Sequence ID:NM_001130678
NM_001130679
NM_001968
Entrez Gene ID:1977
Ensembl ID:ENSG00000151247

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q21-q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 99807501 - 99850279

 Exon Info From UCSC:
NM_001130678
NM_001130679
NM_001968

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4282826Full LengthBC012611eukaryotic translation initiation factor 4E
5265600Full LengthBC035166eukaryotic translation initiation factor 4E
5295521Full LengthBC043226eukaryotic translation initiation factor 4E
6716042Full LengthBC107715eukaryotic translation initiation factor 4E

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001959  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001130678 NP_001124150    
NM_001130679 NP_001124151    
NM_001968 NP_001959 P06730 IF4E

Related Sequences

 
mRNAGenPeptSwissProt
M15353 AAC13647 P06730
BC012611 AAH12611 P06730
BC035166 AAH35166 P06730
BC043226 AAH43226 P06730
BC107715 AAI07716 Q32Q75
DQ890728 ABM81654  
DQ893903 ABM84829  
AK300982 BAH13387 P06730

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF4E NP_001124150 R.norvegicus Eif4e 117045   NP_446426 98
M.musculus Eif4e 13684 Gene Info NP_031943 98
A.gambiae AgaP_AGAP007172 1269944   XP_308598 53
D.melanogaster eIF4E-7 31059   NP_726718 50
D.melanogaster eIF-4E 45525   NP_729484 48
D.melanogaster eIF4E-4 38743   NP_648052 47
D.melanogaster eIF4E-5 38878   NP_648160 44
A.thaliana EIF4E 827529   NP_193538 44
D.melanogaster eIF4E-3 38923   NP_648194 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta