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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. UCP1, uncoupling protein 1 (mitochondrial, proton carrier)
Sequence ID:NM_021833
RefSeqGene ID:NG_012139
Entrez Gene ID:7350
Ensembl ID:ENSG00000109424

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
OBESITYADRB2
ADRB3
AGRP
CARTPT
ENPP1
FTO
GHRL
MC3R
MC4R
NR0B2
POMC
PPARG
PPARGC1B
PYY
SDC3
SIM1
UCP2
UCP3
UCP3

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q28-q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 141481050 - 141489959

NM_021833 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
3115141481051141481163
116296141483346141483526
297398141484263141484364
399599141484471141484671
600798141488932141489130
7991000141489757141489958

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40016000Full LengthBC098352uncoupling protein 1 (mitochondrial, proton carrier)
40016001Full LengthBC098258uncoupling protein 1 (mitochondrial, proton carrier)
40016002Full LengthBC098168uncoupling protein 1 (mitochondrial, proton carrier)
40016003Full LengthBC096736uncoupling protein 1 (mitochondrial, proton carrier)
7262268IncompleteBC069556uncoupling protein 1 (mitochondrial, proton carrier)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_068605  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_021833 NP_068605 P25874 Mito_carr

Related Sequences

 
mRNAGenPeptSwissProt
U28480 AAA85271 P25874
BC069556 AAH69556 P25874
BC096736 AAH96736 Q4KMT7
BC098168 AAH98168 P25874
BC098258 AAH98258 P25874
BC098352 AAH98352 Q4KMT7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens UCP1 NP_068605 M.musculus Ucp1 22227 Gene Info NP_033489 80
R.norvegicus Ucp1 24860   NP_036814 80

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)