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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CASP1, caspase 1, apoptosis-related cysteine peptidase
Sequence ID:NM_001223
NM_001257118
NM_001257119
NM_033292
NM_033293
NM_033294
NM_033295
RefSeqGene ID:NG_029124
Entrez Gene ID:834
Ensembl ID:ENSG00000137752

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 104901171 - 104905202

 Exon Info From UCSC:
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5477096Full LengthBC062327caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
5583549IncompleteBC041689caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001214  NP_150636  NP_150635  NP_150637  NP_150634  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001223 NP_001214     CARD
Peptidase_C14
NM_001257118 NP_001244047      
NM_001257119 NP_001244048      
NM_033292 NP_150634 P29466 EC 3.4.22.36 CARD
Peptidase_C14
NM_033293 NP_150635     Peptidase_C14
NM_033294 NP_150636     Peptidase_C14
NM_033295 NP_150637     Peptidase_C14

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M87507 AAA66942 P29466 EC 3.4.22.36
U13697 AAC50107 P29466 EC 3.4.22.36
U13698 AAC50108 P29466 EC 3.4.22.36
U13699 AAC50109 P29466 EC 3.4.22.36
U13700 AAC50110 P29466 EC 3.4.22.36
BC041689 AAH41689 P29466 EC 3.4.22.36
BC062327 AAH62327 P29466 EC 3.4.22.36
AY660536 AAT72297 P29466 EC 3.4.22.36
HQ447656 ADQ32141    
AB102878 BAD89407 Q5FBZ0  
AK223503 BAD97223 P29466 EC 3.4.22.36
AK290114 BAF82803 A8K249  
AK290122 BAF82811 A8K257  
AK313516 BAG36296 B2R8U9  
AK296646 BAG59246 B4DKN4  
AK301037 BAG62650 B4DVD8  
X65019 CAA46153 P29466 EC 3.4.22.36

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CASP1 NP_150634 R.norvegicus Casp1 25166   NP_036894 63
M.musculus Casp1 12362 Gene Info NP_033937 62

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta