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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ITGAX, integrin, alpha X (complement component 3 receptor 4 subunit)
Sequence ID:NM_000887
RefSeqGene ID:NG_011451
Entrez Gene ID:3687
Ensembl ID:ENSG00000140678

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
?SYSTEMIC LUPUS ERYTHEMATOSUS, OR PROTECTION AGAINSTBANK1
C4A
C4A
DNASE1
DNASE1
FASLG
FCGR2B
FCGR3A
PDCD1
PTPN22
STAT4
STAT4
TREX1
TREX1
TREX1

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 31373134 - 31382652

 Exon Info From UCSC:
NM_000887

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5745308Full LengthBC038237integrin, alpha X (complement component 3 receptor 4 subunit)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000878  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000887 NP_000878 P20702 VWA
Integrin_alpha
FG-GAP
Integrin_alpha2

Related Sequences

 
mRNAGenPeptSwissProt
M81695 AAA59180 P20702
BC038237 AAH38237 P20702
DQ892486 ABM83412  
DQ895697 ABM86623  
AK074047 BAB84873 Q8TES5
AK293367 BAG56881 B4DDX0
AK296666 BAG59263 B4DKQ1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ITGAX NP_000878 R.norvegicus Itgax 499271   XP_574569 72
M.musculus Itgax 16411 Gene Info NP_067309 71

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta