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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. KCNJ11, potassium inwardly-rectifying channel, subfamily J, member 11
Sequence ID:NM_000525
NM_001166290
RefSeqGene ID:NG_012446
Entrez Gene ID:3767
Ensembl ID:ENSG00000187486

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
AKT2
CDKAL1
ENPP1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
HNF4A
IGF2BP2
IL6
IRS1
IRS2
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WFS1
WFS1
DIABETES MELLITUS, PERMANENT NEONATALABCC8
GCK
INS
DIABETES MELLITUS, TRANSIENT NEONATAL, 3 
HYPERINSULINEMIC HYPOGLYCEMIA, FAMILIAL, 2 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 17408251 - 17410878

 Exon Info From UCSC:
NM_000525
NM_001166290

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6279724Full LengthBC064497potassium inwardly-rectifying channel, subfamily J, member 11
40032947Full LengthBC112358potassium inwardly-rectifying channel, subfamily J, member 11
5723755IncompleteBC040617potassium inwardly-rectifying channel, subfamily J, member 11

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000516  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000525 NP_000516   IRK
NM_001166290 NP_001159762    

Related Sequences

 
mRNAGenPeptSwissProt
BC040617 AAH40617 Q8IW96
BC064497 AAH64497 Q14654
BC112358 AAI12359 Q14654
AK314943 BAG37449 B2RC52
AK301550 BAG63046 B4DWI4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens KCNJ11 NP_000516 M.musculus Kcnj11 16514 Gene Info NP_034732 96
R.norvegicus Kcnj11 83535   NP_112648 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)