Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CTLA4, cytotoxic T-lymphocyte-associated protein 4
Sequence ID:NM_001037631
NM_005214
RefSeqGene ID:NG_011502
Entrez Gene ID:1493
Ensembl ID:ENSG00000163599

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CELIAC DISEASE 
DIABETES MELLITUS, INSULIN-DEPENDENT 
HYPOTHYROIDISM,AUTOIMMUNE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q33Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 204732510 - 204738683

 Exon Info From UCSC:
NM_001037631
NM_005214

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262243Full LengthBC069566cytotoxic T-lymphocyte-associated protein 4
30417685Full LengthBC070162cytotoxic T-lymphocyte-associated protein 4
30915247Full LengthBC074893cytotoxic T-lymphocyte-associated protein 4
30915552Full LengthBC074842cytotoxic T-lymphocyte-associated protein 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005205  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001037631 NP_001032720    
NM_005214 NP_005205 P16410 V-set

Related Sequences

 
mRNAGenPeptSwissProt
L15006 AAB59385 P16410
U90273 AAD00698 O95653
BC069566 AAH69566 Q6GR94
BC070162 AAH70162 Q6GR94
BC074842 AAH74842 P16410
BC074893 AAH74893 P16410
AF414120 AAL07473 P16410
AF486806 AAL96664 Q8TDA6
AY209009 AAO17066 Q6GR94
AY792514 AAV66331 P16410
AY999702 AAY00166 P16410
DQ785106 ABG85285 P16410
AK313732 BAG36473 Q6GR94

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CTLA4 NP_005205 R.norvegicus Ctla4 63835   NP_113862 76
M.musculus Ctla4 12477 Gene Info NP_033973 75

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta