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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. FBLN1, fibulin 1
Sequence ID:NM_001996
NM_006485
NM_006486
NM_006487
RefSeqGene ID:NG_023308
Entrez Gene ID:2192
Ensembl ID:ENSG00000077942

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
SYNPOLYDACTYLY, 3/3'4, ASSOCIATED WITH METACARPAL AND METATARSALSYNOSTOSES 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 45898855 - 45997013

 Exon Info From UCSC:
NM_001996
NM_006485
NM_006486
NM_006487

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4819750Full LengthBC022497fibulin 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006477  NP_006476  NP_006478  NP_001987  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001996 NP_001987   EGF
ANATO
TIL
EGF_CA
NM_006485 NP_006476   EGF
ANATO
TIL
EGF_CA
NM_006486 NP_006477   EGF
ANATO
TIL
EGF_CA
NM_006487 NP_006478   EGF
ANATO
TIL
EGF_CA

Related Sequences

 
mRNAGenPeptSwissProt
U01244 AAB17099 P23142
AF217999 AAG17241 P23142
BC022497 AAH22497 P23142
AF126110 AAK37822 P23142
DQ894047 ABM84973  
AK075566 BAC11705 Q8NBH6
AK300806 BAG62463 B4DUV1
AK316291 BAH14662 B4DUV1
X53741 CAA37770 P23142
X53742 CAA37771 P23142
X53743 CAA37772 P23142

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FBLN1 NP_006477 R.norvegicus Fbln1 315191   NP_001121019 87
M.musculus Fbln1 14114 Gene Info NP_034310 85
C.elegans fibrulin-1D 177788   NP_501694 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)