Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SPG21, Spastic paraplegia 21 (autosomal recessive, Mast syndrome)
Sequence ID:NM_016630
NM_001127890
NM_001127889
RefSeqGene ID:NG_008992
Entrez Gene ID:51324
Ensembl ID:ENSG00000090487

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MAST SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q21-q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 65255366 - 65275928

 Exon Info From UCSC:
NM_016630
NM_001127890
NM_001127889

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3357388Full LengthBC000244spastic paraplegia 21 (autosomal recessive, Mast syndrome)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057714  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001127889 NP_001121361    
NM_001127890 NP_001121362    
NM_016630 NP_057714 Q9NZD8 Abhydrolase_1

Related Sequences

 
mRNAGenPeptSwissProt
AF208861 AAF64275 Q9NZD8
BC000244 AAH00244 Q9NZD8
AF212231 AAK14917 Q9NZD8
HQ447370 ADQ31856  
AK172849 BAD18813 Q9NZD8
AK301362 BAG62906 Q9NZD8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SPG21 NP_057714 M.musculus Spg21 27965 Gene Info NP_613050 98
R.norvegicus Spg21 300791   NP_001006988 97
A.thaliana AT4G12230 826831   NP_192960 47

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)