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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MMP14, matrix metallopeptidase 14 (membrane-inserted)
Sequence ID:NM_004995
Entrez Gene ID:4323
Ensembl ID:ENSG00000157227

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:14q11-q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 23305799 - 23316970

NM_004995 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
13422330579223306133
3434912331069923310847
4926142331112123311243
6159222331161823311925
92310842331246523312626
108512452331291823313078
124613842331357923313717
138515352331383823313988
153616512331445923314574
165235372331491623316801

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6046773Full LengthBC064803matrix metallopeptidase 14 (membrane-inserted)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004986  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004995 NP_004986 P50281 EC 3.4.24.80 Hemopexin
Peptidase_M10
PG_binding_1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U41078 AAA83770 P50281 EC 3.4.24.80
BC064803 AAH64803 P50281 EC 3.4.24.80
D26512 BAA05519 P50281 EC 3.4.24.80
AK291325 BAF84014 P50281 EC 3.4.24.80
AK312657 BAG35540 B2R6P3  
X83535 CAA58519 P50281 EC 3.4.24.80
X90925 CAA62432 P50281 EC 3.4.24.80
Z48481 CAA88372 P50281 EC 3.4.24.80
HE978355 CCK73138    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MMP14 NP_004986 M.musculus Mmp14 17387 Gene Info NP_032634 97
R.norvegicus Mmp14 81707   NP_112318 97
A.gambiae AgaP_AGAP006904 1270173   XP_001688107 41
D.melanogaster Mmp1 37949   NP_726473 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta