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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PIK3CB, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Sequence ID:NM_001256045
Entrez Gene ID:5291
Ensembl ID:ENSG00000051382

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 138373929 - 138426463

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40008544Full LengthBC114432phosphoinositide-3-kinase, catalytic, beta polypeptide
3447173IncompleteBC003393phosphoinositide-3-kinase, catalytic, beta polypeptide
4291567IncompleteBC022049phosphoinositide-3-kinase, catalytic, beta polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006210  

Protein Infomation

NM_001256045 NP_001242974      
NM_006219 NP_006210 P42338 EC PI3_PI4_kinase

Related Sequences

S67334 AAB29081 P42338 EC
BC003393 AAH03393 Q9BTS4  
BC022049 AAH22049 Q6PJ60  
BC114432 AAI14433 P42338 EC
AK293754 BAG57175 B4DER4  
AK302937 BAG64095 B4DZI3  
CR749357 CAH18210 Q68DL0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PIK3CB NP_006210 M.musculus Pik3cb 74769 Gene Info NP_083370 96
R.norvegicus Pik3cb 85243   NP_445933 96
A.gambiae AgaP_AGAP000018 1272257   XP_311141 43
D.melanogaster Pi3K92E 42446   NP_732536 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)