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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PIK3CB, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Sequence ID:NM_001256045
NM_006219
Entrez Gene ID:5291
Ensembl ID:ENSG00000051382

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:3q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 138373929 - 138426463


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40008544Full LengthBC114432phosphoinositide-3-kinase, catalytic, beta polypeptide
3447173IncompleteBC003393phosphoinositide-3-kinase, catalytic, beta polypeptide
4291567IncompleteBC022049phosphoinositide-3-kinase, catalytic, beta polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006210  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001256045 NP_001242974      
NM_006219 NP_006210 P42338 EC 2.7.1.153 PI3_PI4_kinase
PI3Ka
PI3K_C2
PI3K_rbd
PI3K_p85B

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
S67334 AAB29081 P42338 EC 2.7.1.153
BC003393 AAH03393 Q9BTS4  
BC022049 AAH22049 Q6PJ60  
BC114432 AAI14433 P42338 EC 2.7.1.153
AK293754 BAG57175 B4DER4  
AK302937 BAG64095 B4DZI3  
CR749357 CAH18210 Q68DL0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PIK3CB NP_006210 M.musculus Pik3cb 74769 Gene Info NP_083370 96
R.norvegicus Pik3cb 85243   NP_445933 96
A.gambiae AgaP_AGAP000018 1272257   XP_311141 43
D.melanogaster Pi3K92E 42446   NP_732536 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)