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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CCNB1, Cyclin B1
Sequence ID:NM_031966
Entrez Gene ID:891
Ensembl ID:ENSG00000134057

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 68462948 - 68473581

NM_031966 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11986846291268463109
1993696846373468463904
3705406846399968464169
5417236846709668467278
7248826847007768470235
88311196847070368470939
112012606847122368471363
126113716847306568473175
137220876847335068474065

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2963100Full LengthBC006510cyclin B1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_114172  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_031966 NP_114172 P14635 Cyclin_N
Cyclin_C

Related Sequences

 
mRNAGenPeptSwissProt
BC006510 AAH06510 P14635
AY027761 AAK27417 Q9BWV0
AY027762 AAK27418 Q9BWU9
AY027763 AAK27419 Q9BPX9
AY027764 AAK27420 Q9BWU8
AY027765 AAK27421 Q9BPX9
AY027767 AAK27422 Q9BPX9
AY027768 AAK27423 Q9BPX9
AY027769 AAK27424 Q9BPX9
AY027770 AAK27425 Q9BWU7
BT020128 AAV38930 Q5TZP9
DQ892975 ABM83901  
AK289431 BAF82120 A8K066
AM851053 CAO99273 H1UBN2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CCNB1 NP_114172 R.norvegicus Ccnb1 25203   NP_741988 87
A.gambiae AgaP_AGAP004963 1275774   XP_315060 48
A.gambiae AgaP_AGAP004962 1275773   XP_315059 48
S.pombe cdc13 2540880   NP_595171 44
S.cerevisiae CLB2 856236   NP_015444 42
D.melanogaster CycB 37618   NP_726246 38
N.crassa NCU02758 3880000   XP_963851 38
A.thaliana CYCB1;4 817217   NP_180244 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta