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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ZAP70, zeta-chain (TCR) associated protein kinase 70kDa
Sequence ID:NM_001079
NM_207519
RefSeqGene ID:NG_007727
Entrez Gene ID:7535
Ensembl ID:ENSG00000115085

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
SELECTIVE T-CELL DEFECT 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 98350868 - 98355961

 Exon Info From UCSC:
NM_001079
NM_207519

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5168073Full LengthBC039039zeta-chain (TCR) associated protein kinase 70kDa
5757161Full LengthBC053878zeta-chain (TCR) associated protein kinase 70kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_997402  NP_001070  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001079 NP_001070 P43403 EC 2.7.10.2 SH2
Pkinase_Tyr
NM_207519 NP_997402     Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC039039 AAH39039 P43403 EC 2.7.10.2
BC053878 AAH53878 P43403 EC 2.7.10.2
AB083211 BAC43747 P43403 EC 2.7.10.2
AK303341 BAG64404 B4E0E2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ZAP70 NP_001070 M.musculus Zap70 22637 Gene Info NP_033565 94
R.norvegicus Zap70 301348   NP_001012002 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta