Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HFE, hemochromatosis
Sequence ID:NM_000410
NM_139003
NM_139004
NM_139006
NM_139007
NM_139008
NM_139009
NM_139010
NM_139011
NM_139002
NM_139005
RefSeqGene ID:NG_008720
Entrez Gene ID:3077
Ensembl ID:ENSG00000010704

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ALZHEIMER DISEASEA2M
ACE
APBB2
APP
BLMH
MPO
NOS3
PAXIP1
PLAU
SORL1
HEMOCHROMATOSISBMP2
MICROVASCULAR COMPLICATIONS OF DIABETES7 
PORPHYRIA CUTANEA TARDAUROD
PORPHYRIA VARIEGATAPPOX
[TRANSFERRIN SERUM LEVEL QTL2] 

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 26087632 - 26094458

 Exon Info From UCSC:
NM_000410
NM_139003
NM_139004
NM_139006
NM_139007
NM_139008
NM_139009
NM_139010
NM_139011

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915171Full LengthBC074721hemochromatosis
40125752Full LengthBC117201hemochromatosis
40125754Full LengthBC117203hemochromatosis

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_620573  NP_620579  NP_620575  NP_620578  NP_620572  NP_620576  NP_000401  NP_620577  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000410 NP_000401 Q30201 MHC_I
C1-set
NM_139003 NP_620572   ig
MHC_I
C1-set
NM_139004 NP_620573   ig
MHC_I
C1-set
NM_139006 NP_620575   ig
MHC_I
C1-set
NM_139007 NP_620576   ig
MHC_I
C1-set
NM_139008 NP_620577   ig
MHC_I
C1-set
NM_139009 NP_620578   ig
MHC_I
C1-set
NM_139010 NP_620579   ig
C1-set
NM_139011 NP_620580    

Related Sequences

 
mRNAGenPeptSwissProt
U60319 AAC51823 Q30201
AF079407 AAC62646 Q30201
AF079408 AAC62647 Q30201
AF079409 AAC62648 Q30201
AF109385 AAD52104 Q9TQ79
AF149804 AAG29342 Q30201
AF115264 AAG29571 Q30201
AF115265 AAG29572 Q30201
AF144240 AAG29575 Q30201
AF144242 AAG29577 Q30201
BC074721 AAH74721 Q6B0J5
BC117201 AAI17202 Q30201
BC117203 AAI17204 Q30201
AY205604 AAO47091 Q86WL1
HQ258197 ADR82951  
JN375752 AEO50365 G3LGQ4
JN375753 AEO50366 G3LGQ5
JN375754 AEO50367 G3LGQ6
JN375755 AEO50368 G3LGQ7
JN375756 AEO50369 G3LGR0
JN375757 AEO50370 G3LGQ9
JN375758 AEO50371 G3LGR0
JN375759 AEO50372 G3LGR1
AK293393 BAG56902 B4DDZ1
AK300933 BAG62562 B4DV50
AK316502 BAH14873 B7ZB37
AJ249335 CAC67792 Q30201
AJ249336 CAC67793 Q30201
AJ249337 CAC67794 Q30201
AJ249338 CAC67795 Q30201
AJ250635 CAC80805 Q30201

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HFE NP_000401 R.norvegicus Hfe 29199   NP_445753 71
M.musculus Hfe 15216 Gene Info NP_034554 69

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)