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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ME2, malic enzyme 2, NAD(+)-dependent, mitochondrial
Sequence ID:NM_001168335
NM_002396
RefSeqGene ID:NG_016198
Entrez Gene ID:4200
Ensembl ID:ENSG00000082212

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPSY, IDIOPATHIC GENERALIZEDCACNB4
OPIOID DEPENDENCE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:18q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:18: 48452214 - 48474267

 Exon Info From UCSC:
NM_001168335
NM_002396

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2900677Full LengthBC000147malic enzyme 2, NAD(+)-dependent, mitochondrial

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002387  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001168335 NP_001161807      
NM_002396 NP_002387 P23368 EC 1.1.1.38 malic
Malic_M

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M55905 AAA36197 P23368 EC 1.1.1.38
BC000147 AAH00147 P23368 EC 1.1.1.38
AK313391 BAG36189 P23368 EC 1.1.1.38
AJ294818 CAC14574 P23368 EC 1.1.1.38

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ME2 NP_002387 M.musculus Me2 107029 Gene Info NP_663469 89
R.norvegicus Me2 307270   NP_001100846 89
A.thaliana NADP-ME3 832657   NP_197960 52
A.thaliana NADP-ME2 831039   NP_196728 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)