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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. CHRNB2, Cholinergic receptor, nicotinic, beta 2 (neuronal)
Sequence ID:NM_000748
RefSeqGene ID:NG_008027
Entrez Gene ID:1141
Ensembl ID:ENSG00000160716

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPSY, NOCTURNAL FRONTAL LOBE, 3 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 154540487 - 154548408

NM_000748 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1328154540256154540583
329474154541937154542082
475519154542267154542311
520629154542733154542842
6301602154543664154544636
16035716154548237154552350

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915357Full LengthBC075040cholinergic receptor, nicotinic, beta 2 (neuronal)
30915573Full LengthBC075041cholinergic receptor, nicotinic, beta 2 (neuronal)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000739  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000748 NP_000739 Q5SXY3
P17787
Neur_chan_LBD
Neur_chan_memb

Related Sequences

 
mRNAGenPeptSwissProt
U62437 AAB40115 Q5SXY3
P17787
BC075040 AAH75040 Q5SXY3
P17787
BC075041 AAH75041 Q5SXY3
P17787
AK313470 BAG36255 Q5SXY3
X53179 CAA37320 Q5SXY3
P17787
Y08415 CAA69692 Q5SXY3
P17787

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CHRNB2 NP_000739 R.norvegicus Chrnb2 54239   NP_062170 95
M.musculus Chrnb2 11444 Gene Info NP_033732 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)