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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. HIST2H2BE, Histone cluster 2, H2be
Sequence ID:NM_003528
Entrez Gene ID:8349
Ensembl ID:ENSG00000184678

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q21.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 149856011 - 149858231

NM_003528 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2989788Full LengthBC005827histone cluster 2, H2be
3936695Full LengthBC069193histone cluster 2, H2be
40002353Full LengthBC096121histone cluster 2, H2be
40014245Full LengthBC098112histone cluster 2, H2be
40014249Full LengthBC098289histone cluster 2, H2be
40014260Full LengthBC107084histone cluster 2, H2be
40014264Full LengthBC107085histone cluster 2, H2be

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003519  

Protein Infomation

NM_003528 NP_003519 Q16778 Histone

Related Sequences

M60756 AAA63192 Q16778
BC005827 AAH05827 Q16778
BC069193 AAH69193 Q16778
BC096121 AAH96121 Q16778
BC098112 AAH98112 Q16778
BC098289 AAH98289 Q16778
BC107084 AAI07085 Q16778
BC107085 AAI07086 Q16778
HQ447538 ADQ32024  
AK289725 BAF82414 Q16778
CR541895 CAG46693 Q16778

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens HIST2H2BE NP_003519 H.sapiens HIST1H2BC 8347 Gene Info NP_003517 99
H.sapiens HIST1H2BI 8346 Gene Info NP_003516 99
H.sapiens HIST1H2BE 8344 Gene Info NP_003514 99
H.sapiens HIST1H2BF 8343 Gene Info NP_003513 99
H.sapiens HIST1H2BG 8339 Gene Info NP_003509 99
M.musculus Hist1h2bg 319181 Gene Info NP_835503 99
M.musculus Hist1h2be 319179 Gene Info NP_001171124 99
M.musculus Hist1h2bc 68024 Gene Info NP_075911 99
R.norvegicus Hist1h2bl 64647   NP_072173 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)