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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. YARS, tyrosyl-tRNA synthetase
Sequence ID:NM_003680
RefSeqGene ID:NG_008408
Entrez Gene ID:8565
Ensembl ID:ENSG00000134684

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CHARCOT-MARIE-TOOTH DISEASE, DOMINANT INTERMEDIATE C 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p35.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 33240841 - 33282928

 Exon Info From UCSC:
NM_003680

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2821104Full LengthBC001933tyrosyl-tRNA synthetase
2821104Full LengthBC004151tyrosyl-tRNA synthetase
4386850Full LengthBC016689tyrosyl-tRNA synthetase
4837840IncompleteBC035242tyrosyl-tRNA synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003671  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003680 NP_003671 P54577 EC 6.1.1.1 tRNA-synt_1b
tRNA_bind

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U40714 AAB39406 P54577 EC 6.1.1.1
U89436 AAB88409 P54577 EC 6.1.1.1
BC001933 AAH01933 P54577 EC 6.1.1.1
BC004151 AAH04151 P54577 EC 6.1.1.1
BC016689 AAH16689 P54577 EC 6.1.1.1
DQ891666 ABM82592    
DQ894853 ABM85779    
AK223608 BAD97328 P54577 EC 6.1.1.1
AK125213 BAG54166 P54577 EC 6.1.1.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens YARS NP_003671 M.musculus Yars 107271 Gene Info NP_598912 97
R.norvegicus Yars 313047   NP_001020867 95
D.melanogaster Aats-tyr 39829   NP_648895 70
A.gambiae AgaP_AGAP003003 1272950   XP_311880 62
S.cerevisiae TYS1 853097   NP_011701 58
S.pombe yrs1 2539269   NP_587876 56
N.crassa NCU07755 3874686   XP_958548 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)