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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. EPHX2, epoxide hydrolase 2, cytoplasmic
Sequence ID:NM_001256482
NM_001256483
NM_001256484
NM_001979
RefSeqGene ID:NG_012064
Entrez Gene ID:2053
Ensembl ID:ENSG00000120915

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CORONARY ARTERY DISEASE IN FAMILIAL HYPERCHOLESTEROLEMIA, PROTECTION AGAINSTABCA1
APOA2
GHR
GHR
GHR
ITIH4
LDLR
LDLR
PPP1R17

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 27348691 - 27402120


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3938557Full LengthBC013874epoxide hydrolase 2, cytoplasmic
3946158Full LengthBC007708epoxide hydrolase 2, cytoplasmic
4053931Full LengthBC011628epoxide hydrolase 2, cytoplasmic

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001970  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001256482 NP_001243411      
NM_001256483 NP_001243412      
NM_001256484 NP_001243413      
NM_001979 NP_001970 P34913 EC 3.3.2.10
EC 3.1.3.76
Abhydrolase_1
Hydrolase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L05779 AAA02756 P34913 EC 3.3.2.10
EC 3.1.3.76
AF233334 AAG14966 P34913 EC 3.3.2.10
EC 3.1.3.76
AF233335 AAG14967 P34913 EC 3.3.2.10
EC 3.1.3.76
AF233336 AAG14968 P34913 EC 3.3.2.10
EC 3.1.3.76
BC007708 AAH07708 P34913 EC 3.3.2.10
EC 3.1.3.76
BC011628 AAH11628 P34913 EC 3.3.2.10
EC 3.1.3.76
BC013874 AAH13874 P34913 EC 3.3.2.10
EC 3.1.3.76
BT006885 AAP35531 P34913 EC 3.3.2.10
EC 3.1.3.76
DQ892749 ABM83675    
DQ895995 ABM86963    
AK096089 BAG53210 B3KTU8  
AK096770 BAG53362 B3KUA0  
AK294065 BAG57410 B4DFE9  
AK303904 BAG64834 B4E1M2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EPHX2 NP_001970 R.norvegicus Ephx2 65030   NP_075225 73
M.musculus Ephx2 13850 Gene Info NP_031966 73
A.thaliana AT3G51000 824264   NP_190669 37
N.crassa NCU00350 3873871   XP_957821 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta