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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SMC1A, structural maintenance of chromosomes 1A
Sequence ID:NM_006306
RefSeqGene ID:NG_006988
Entrez Gene ID:8243
Ensembl ID:ENSG00000072501

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp11.22-p11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 53439950 - 53449576

 Exon Info From UCSC:
NM_006306

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8327595Full LengthBC112127structural maintenance of chromosomes 1A
5583513IncompleteBC064368structural maintenance of chromosomes 1A
6069353IncompleteBC080185structural maintenance of chromosomes 1A

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006297  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_006306 NP_006297 Q14683 SMC_N
SMC_hinge

Related Sequences

 
mRNAGenPeptSwissProt
S78271 AAB34405 Q14683
BC064368 AAH64368 Q6P2R1
BC080185 AAH80185 Q68EN4
BC112127 AAI12128 Q14683
AF176781 AAQ13659 Q7Z4C6
HQ258690 ADR83441  
D80000 BAA11495 Q14683
AK291921 BAF84610 A8K7A6
AK301266 BAH13445 B7Z709
BX640922 CAE45960 Q6MZR8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SMC1A NP_006297 R.norvegicus Smc1a 63996   NP_113871 100
M.musculus Smc1a 24061 Gene Info NP_062684 100
A.gambiae AgaP_AGAP002947 1273015   XP_311953 51
D.melanogaster SMC1 42853   NP_651211 50
C.elegans him-1 172116   NP_001040658 43
A.thaliana TTN8 824632   NP_001190092 39
S.pombe psm1 2540557   NP_596049 35
N.crassa NCU01323 3877569   XP_961409 35
S.cerevisiae SMC1 850540   NP_116647 32

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)