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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ME1, malic enzyme 1, NADP(+)-dependent, cytosolic
Sequence ID:NM_002395
Entrez Gene ID:4199
Ensembl ID:ENSG00000065833

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:6q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 83920124 - 83921473

 Exon Info From UCSC:
NM_002395

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4870714Full LengthBC025246malic enzyme 1, NADP(+)-dependent, cytosolic
4290619IncompleteBC017403malic enzyme 1, NADP(+)-dependent, cytosolic

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002386  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002395 NP_002386 P48163 EC 1.1.1.40 malic
Malic_M

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L34035 AAB01380 P48163 EC 1.1.1.40
U43944 AAC50613 P48163 EC 1.1.1.40
BC017403 AAH17403 Q8WVX2  
BC025246 AAH25246 P48163 EC 1.1.1.40
DQ892155 ABM83081    
EU176687 ABW03488    
AK223417 BAD97137 P48163 EC 1.1.1.40
AK289783 BAF82472 A8K168  
AK301875 BAG63311 B4DX99  
AK302777 BAG63982 B4DZ70  
X77244 CAA54460 P48163 EC 1.1.1.40

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ME1 NP_002386 M.musculus Me1 17436 Gene Info NP_032641 90
R.norvegicus Me1 24552   NP_036732 90
A.gambiae AgaP_AGAP004159 1273984   XP_313043 58
D.melanogaster Mdh 43936   NP_651959 57
A.thaliana NADP-ME1 816509   NP_179580 52
N.crassa NCU02906 3881768   XP_965588 42
S.cerevisiae MAE1 853839   NP_012896 40
S.pombe mae2 2539592   NP_587760 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta