Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PSMC4, proteasome (prosome, macropain) 26S subunit, ATPase, 4
Sequence ID:NM_006503
Entrez Gene ID:5704
Ensembl ID:ENSG00000013275

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.11-q13.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 40477069 - 40487348

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2823007Full LengthBC000343proteasome (prosome, macropain) 26S subunit, ATPase, 4
4046205Full LengthBC010396proteasome (prosome, macropain) 26S subunit, ATPase, 4
4899042Full LengthBC014488proteasome (prosome, macropain) 26S subunit, ATPase, 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006494  

Protein Infomation

NM_006503 NP_006494 P43686 AAA
NM_153001 NP_694546    

Related Sequences

AF038965 AAC26843 P43686
AF020736 AAC32612 P43686
U27515 AAC99817 P43686
BC000343 AAH00343 P43686
BC010396 AAH10396 P43686
BC014488 AAH14488 P43686
BT007232 AAP35896 P43686
DQ891875 ABM82801  
DQ894876 ABM85802  
AK290285 BAF82974 A8K2M0
AK313183 BAG36000 A8K2M0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PSMC4 NP_006494 M.musculus Psmc4 23996 Gene Info NP_036004 100
R.norvegicus Psmc4 117262   NP_476463 100
A.gambiae AgaP_AGAP003008 1272945   XP_311871 92
D.melanogaster Rpt3 32047   NP_572686 89
C.elegans rpt-3 175925   NP_498429 83
A.thaliana RPT3 835941   NP_200637 80
N.crassa NCU02260 3876090   XP_959904 75
S.pombe rpt3 2539539   NP_588437 75
P.falciparum PFD0665c 812570   XP_001351444 69
S.cerevisiae RPT3 852003   NP_010682 69

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)