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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HERC1, HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Sequence ID:NM_003922
Entrez Gene ID:8925
Ensembl ID:ENSG00000103657

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, soft tissue, spleen, stem cell, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 63900817 - 64025201

 Exon Info From UCSC:
NM_003922

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4472317IncompleteBC040929hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
9094485IncompleteBC172909hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
9094486IncompleteBC172910hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003913  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003922 NP_003913 Q15751 WD40
RCC1
SPRY
HECT

Related Sequences

 
mRNAGenPeptSwissProt
U50078 AAD12586 Q15751
BC040929 AAH40929 Q15751
AK296690 BAG59284 B4DKS2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HERC1 NP_003913 M.musculus Herc1 235439 Gene Info NP_663592 97
R.norvegicus Herc1 315771   XP_236362 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)