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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TDP1, tyrosyl-DNA phosphodiesterase 1
Sequence ID:NM_001008744
NM_018319
RefSeqGene ID:NG_009164
Entrez Gene ID:55775
Ensembl ID:ENSG00000042088

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE WITH AXONAL NEUROPATHY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q32.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 90429473 - 90455378

 Exon Info From UCSC:
NM_001008744
NM_018319

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3900062Full LengthBC015474tyrosyl-DNA phosphodiesterase 1
6597752Full LengthBC107877tyrosyl-DNA phosphodiesterase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001008744  NP_060789  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001008744 NP_001008744 Q9NUW8 Tyr-DNA_phospho
NM_018319 NP_060789 Q9NUW8 Tyr-DNA_phospho

Related Sequences

 
mRNAGenPeptSwissProt
AF182002 AAF65623 Q9NUW8
AF182003 AAF65624 Q9NUW8
BC006083 AAH06083 Q9BRS7
BC015474 AAH15474 Q9NUW8
BC107877 AAI07878 Q32Q25
AK001952 BAA91997 Q9NUW8
AK315549 BAG37927 B2RDI0
AK023514 BAG51203 B3KN41
BX161451 CAD61915 Q86TV8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TDP1 NP_001008744 M.musculus Tdp1 104884 Gene Info NP_082630 82
R.norvegicus Tdp1 314380   NP_001026827 82
A.thaliana TDP1 831369   NP_197021 40
D.melanogaster gkt 33530   NP_523465 40
A.gambiae AgaP_AGAP010577 1275307   XP_558110 39
C.elegans F52C12.1 176996   NP_500149 39
N.crassa NCU06345 3878518   XP_962379 39
S.pombe tdp1 2539579   NP_587861 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)