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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ESR1, estrogen receptor 1
Sequence ID:NM_000125
NM_001122740
NM_001122741
NM_001122742
RefSeqGene ID:NG_008493
Entrez Gene ID:2099
Ensembl ID:ENSG00000091831

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MIGRAINEEDNRA
TNF
MYOCARDIAL INFARCTIONF13A1
F7
GCLC
GCLM
ITGB3
LGALS2
LRP8
LTA
MIAT
OLR1
PSMA6
THBD
TNFSF4

Cytogenetic Location (from UniGene)

Cytogenetic Location:6q25.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 152129047 - 152420101

 Exon Info From UCSC:
NM_000125
NM_001122740
NM_001122741
NM_001122742

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40128594Full LengthBC128573estrogen receptor 1
40128595Full LengthBC128574estrogen receptor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000116  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000125 NP_000116 P03372 Hormone_recep
zf-C4
Oest_recep
NM_001122740 NP_001116212    
NM_001122741 NP_001116213    
NM_001122742 NP_001116214    

Related Sequences

 
mRNAGenPeptSwissProt
M12674 AAA52399 P03372
M69297 AAA58462 Q14268
U47678 AAB00115 P03372
U68067 AAC51874 Q9UBT1
U68068 AAC51875 Q9UBT1
AF120105 AAD23565 Q9Y2W8
AF258449 AAG41358 Q9H2M2
AF258450 AAG41359 Q9H2M1
AF258451 AAG41360  
BC128573 AAI28574 P03372
BC128574 AAI28575 P03372
AY750962 AAW69860 Q5C8S5
EU921455 ACH41916 B5LY05
EU982838 ACH73261 B5TKC0
EU982839 ACH73262 B5TKC1
EU982840 ACH73263 B5TKC2
FJ147552 ACI01724 B5TZ77
FJ147553 ACI01725 B5TZ78
FJ147554 ACI01726 B5TZ79
FJ147555 ACI01727 B5TZ80
FJ147556 ACI01728 B5TZ81
FJ147557 ACI01729 B5TZ82
FJ147558 ACI01730 B5TZ83
FJ169500 ACI04255 B6DU66
FJ169501 ACI04256 B6DU67
FJ169502 ACI04257 B6DU68
FJ169503 ACI04258 B6DU69
FJ169504 ACI04259 B6DU70
FJ011556 ACI06210 B6DP71
FJ011557 ACI06211 B6DP72
FJ011558 ACI06212 B6DP73
FJ011559 ACI06213 B6DP74
FJ011560 ACI06214 B6DP75
FJ668387 ACN41854 C0L927
FJ712305 ACN66633 C0LJA7
FJ712306 ACN66634 C0LJA8
FJ712307 ACN66635 C0LJA9
FJ716811 ACN89822 C0LLI5
FJ716812 ACN89823 C0LLI6
FJ716813 ACN89824 C0LLI7
FJ716814 ACN89825 C0LLI8
FJ716815 ACN89826 C0LLI9
GQ366704 ACU29456 C7FFR5
GQ411250 ACV41785 C8CJK8
GQ411251 ACV41786 C8CJK9
GQ411253 ACV41788 C8CJL1
GQ411258 ACV41793 C8CJL6
GQ438790 ACV88148 C9E0F0
GQ438791 ACV88149 C9E0F1
JF810888 AEP43755 G4XH65
AK293019 BAF85708 A8KAF4
AK304600 BAG65386 B4E374
AK304833 BAG65577 B4E3R5
AB307713 BAH02304 B6ZGU3
AB588629 BAJ41265 E3WH18
AB588630 BAJ41266 E3WH19
AB685815 BAM62931  
AB685817 BAM62933  
X03635 CAA27284 P03372
X73067 CAA51528 P03372
Z75126 CAA99436 P03372
X03635 CAD97416 A0A4R1
BX640939 CAE45969 P03372

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ESR1 NP_000116 M.musculus Esr1 13982 Gene Info NP_031982 90
R.norvegicus Esr1 24890   NP_036821 89

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta