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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. JAK1, Janus kinase 1
Sequence ID:NM_002227
RefSeqGene ID:NG_023402
Entrez Gene ID:3716
Ensembl ID:ENSG00000162434

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p32.3-p31.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 65299757 - 65352017

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40146751Full LengthBC132729Janus kinase 1 (a protein tyrosine kinase)
4301677IncompleteBC023604Janus kinase 1 (a protein tyrosine kinase)
4608694IncompleteBC111401Janus kinase 1 (a protein tyrosine kinase)
4692472IncompleteBC062431Janus kinase 1 (a protein tyrosine kinase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002218  

Protein Infomation

NM_002227 NP_002218 P23458 EC Pkinase_Tyr

Related Sequences

M64174 AAA36527 P23458 EC
BC023604 AAH23604 Q8IV82  
BC062431 AAH62431 Q6P669  
BC111401 AAI11402 Q0VGA4  
BC132729 AAI32730 P23458 EC
AB209057 BAD92294 P23458 EC
AB219242 BAE02826 Q4LDX3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens JAK1 NP_002218 M.musculus Jak1 16451 Gene Info NP_666257 95
R.norvegicus Jak1 84598   NP_445918 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta