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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FXN, frataxin
Sequence ID:NM_000144
NM_001161706
NM_181425
RefSeqGene ID:NG_008845
Entrez Gene ID:2395
Ensembl ID:ENSG00000165060

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
FRIEDREICH ATAXIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q21.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 71651076 - 71688021

 Exon Info From UCSC:
NM_000144
NM_001161706
NM_181425

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4842134Full LengthBC023633frataxin
5300379Full LengthBC048097frataxin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_852090  NP_000135  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000144 NP_000135 Q16595 EC 1.16.3.1 Frataxin_Cyay
NM_001161706 NP_001155178      
NM_181425 NP_852090     Frataxin_Cyay

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U43747 AAA98510 Q16595 EC 1.16.3.1
BC023633 AAH23633 Q16595 EC 1.16.3.1
BC048097 AAH48097 Q16595 EC 1.16.3.1
HQ447980 ADQ32463    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FXN NP_000135 M.musculus Fxn 14297 Gene Info NP_032070 74
R.norvegicus Fxn 499335   XP_574642 72
S.pombe SPCC1183.03c 2539143   NP_587886 44
A.thaliana FH 828013   NP_192233 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)