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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. UMPS, Uridine monophosphate synthetase
Sequence ID:NM_000373
RefSeqGene ID:NG_017037
Entrez Gene ID:7372
Ensembl ID:ENSG00000114491

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
OROTIC ACIDURIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 124449291 - 124463141

NM_000373 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1262124449212124449473
263416124453939124454092
4171088124456414124457085
10891264124458870124459045
12651379124460998124461112
13806735124462761124468116

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2964556Full LengthBC000364uridine monophosphate synthetase
2964556Full LengthBC007511uridine monophosphate synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000364  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000373 NP_000364 P11172 EC 2.4.2.10
EC 4.1.1.23
Pribosyltran
OMPdecase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J03626 AAA61255 P11172 EC 2.4.2.10
EC 4.1.1.23
M36661 AAA61256 P11172 EC 2.4.2.10
EC 4.1.1.23
BC000364 AAH00364 P11172 EC 2.4.2.10
EC 4.1.1.23
BC007511 AAH07511 P11172 EC 2.4.2.10
EC 4.1.1.23
EU832426 ACE86911    
EU832341 ACE87598    
EU921886 ACH48224 A8K5J1  
EU921887 ACH48225 B5LY64  
EU921888 ACH48226 B5LY64  
EU921889 ACH48227 B5LY64  
EU921890 ACH48228 B5LY67  
EU921891 ACH48229 B5LY68  
EU921892 ACH48230 B5LY69  
EU921893 ACH48231 B5LY70  
EU921894 ACH48232 B5LY71  
EU921895 ACH48233 B5LY72  
D86227 BAA19920 P11172 EC 2.4.2.10
EC 4.1.1.23
D86228 BAA19921 P11172 EC 2.4.2.10
EC 4.1.1.23
D86230 BAA19923 P11172 EC 2.4.2.10
EC 4.1.1.23
AB062285 BAB93468 P11172 EC 2.4.2.10
EC 4.1.1.23
AK291306 BAF83995 A8K5J1  
AL080099 CAB45710 P11172 EC 2.4.2.10
EC 4.1.1.23
CR456787 CAG33068 P11172 EC 2.4.2.10
EC 4.1.1.23

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens UMPS NP_000364 R.norvegicus Umps 288051   NP_001020573 90
M.musculus Umps 22247 Gene Info NP_033497 89
A.thaliana AT3G54470 824612   NP_680130 56
S.cerevisiae URA3 856692   NP_010893 54
S.pombe ura4 2538768   NP_587705 52
A.gambiae AgaP_AGAP004175 1273997   XP_313061 51
D.melanogaster r-l 42493   NP_524427 48
N.crassa NCU03488 3872022   XP_955875 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)