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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. THBD, Thrombomodulin
Sequence ID:NM_000361
RefSeqGene ID:NG_012027
Entrez Gene ID:7056
Ensembl ID:ENSG00000178726

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HEMOLYTIC UREMIC SYNDROME, ATYPICAL 
MYOCARDIAL INFARCTIONESR1
F13A1
F7
GCLC
GCLM
ITGB3
LGALS2
LRP8
LTA
MIAT
OLR1
PSMA6
TNFSF4
THROMBOPHILIA DUE TO THROMBOMODULIN DEFECT 

Cytogenetic Location (from UniGene)

Cytogenetic Location:20p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 23026627 - 23029261

NM_000361 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1840482302627023030300

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5176531Full LengthBC035602thrombomodulin
6007870Full LengthBC053357thrombomodulin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000352  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000361 NP_000352 P07204 EGF
EGF_CA

Related Sequences

 
mRNAGenPeptSwissProt
M16552 AAB59508 P07204
BC035602 AAH35602 P07204
BC053357 AAH53357 P07204
AK123557 BAG53913 B3KVV1
X05495 CAA29045 P07204

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens THBD NP_000352 M.musculus Thbd 21824 Gene Info NP_033404 68
R.norvegicus Thbd 83580   NP_113959 66

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)