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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. DNMT1, DNA (cytosine-5-)-methyltransferase 1
Sequence ID:NM_001130823
RefSeqGene ID:NG_028016
Entrez Gene ID:1786
Ensembl ID:ENSG00000130816

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 10244022 - 10305537

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3077831Full LengthBC092517DNA (cytosine-5-)-methyltransferase 1
8991943Full LengthBC126227DNA (cytosine-5-)-methyltransferase 1
9052613Full LengthBC144093DNA (cytosine-5-)-methyltransferase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001370  

Protein Infomation

NM_001130823 NP_001124295    
NM_001379 NP_001370 P26358 DNA_methylase

Related Sequences

AF180682 AAF23609 P26358
BC092517 AAH92517 I6L9H2
BC126227 AAI26228 P26358
BC144093 AAI44094 P26358
AB209413 BAD92650 Q59FP7
AK122759 BAG53712 B3KVA0
X63692 CAA45219 P26358

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens DNMT1 NP_001124295 R.norvegicus Dnmt1 84350   NP_445806 80
M.musculus Dnmt1 13433 Gene Info NP_034196 79
A.thaliana MET1 834975   NP_199727 39
A.thaliana AT4G08990 826477   NP_192638 37
A.thaliana MEE57 826994   NP_193097 37
A.thaliana DMT2 827052   NP_193150 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)