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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. POLA2, polymerase (DNA directed), alpha 2, accessory subunit
Sequence ID:NM_002689
Entrez Gene ID:23649
Ensembl ID:ENSG00000014138

Database Links

UniGeneEntrez GeneEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 65029460 - 65065095

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822514Full LengthBC001347polymerase (DNA directed), alpha 2 (70kD subunit)
2822514Full LengthBC002990polymerase (DNA directed), alpha 2 (70kD subunit)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002680  

Protein Infomation

NM_002689 NP_002680 Q14181 DNA_pol_E_B

Related Sequences

L24559 AAA16459 Q14181
BC001347 AAH01347 Q14181
BC002990 AAH02990 Q14181
DQ892023 ABM82949  
DQ895215 ABM86141  
AK094569 BAG52888 B3KSX6
AK297842 BAG60176 B4DNB4
CR456737 CAG33018 Q14181

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens POLA2 NP_002680 R.norvegicus Pola2 85242   NP_445932 84
M.musculus Pola2 18969 Gene Info NP_032919 83
A.thaliana POLA2 843086   NP_176930 41
S.pombe spb70 2539135   NP_587765 35
D.melanogaster DNApol-alpha73 43278   NP_733206 32
S.cerevisiae POL12 852245   NP_009518 32
N.crassa NCU03597 3877488   XP_961324 32
A.gambiae AgaP_AGAP004392 1274537   XP_313675 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)