Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CTH, cystathionase (cystathionine gamma-lyase)
Sequence ID:NM_001190463
NM_001902
NM_153742
RefSeqGene ID:NG_008041
Entrez Gene ID:1491
Ensembl ID:ENSG00000116761

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CYSTATHIONINURIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p31.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 70876927 - 70905171

 Exon Info From UCSC:
NM_001190463
NM_001902
NM_153742

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3915913Full LengthBC015807cystathionase (cystathionine gamma-lyase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001893  NP_714964  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001190463 NP_001177392      
NM_001902 NP_001893 P32929 EC 4.4.1.1 Cys_Met_Meta_PP
NM_153742 NP_714964     Cys_Met_Meta_PP

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
S52028 AAB24699 P32929 EC 4.4.1.1
S52784 AAB24700 P32929 EC 4.4.1.1
BC015807 AAH15807 P32929 EC 4.4.1.1
BT006882 AAP35528 P32929 EC 4.4.1.1
EU832398 ACE86883    
EU832313 ACE87570    
AK223376 BAD97096 P32929 EC 4.4.1.1
AK303946 BAG64874 B4E1R2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CTH NP_001893 M.musculus Cth 107869 Gene Info NP_666065 86
R.norvegicus Cth 24962   NP_058770 85
D.melanogaster Eip55E 37143   NP_611352 63
A.gambiae AgaP_AGAP011172 1270758   XP_309478 61
C.elegans ZK1127.10 174155   NP_495449 60
C.elegans F22B8.6 180079   NP_507053 57
S.cerevisiae CYS3 851221   NP_009390 53
N.crassa NCU09230 3879956   XP_963807 52
A.thaliana CBL 824872   NP_191264 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)