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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FLNA, filamin A, alpha
Sequence ID:NM_001110556
NM_001456
RefSeqGene ID:NG_011506
Entrez Gene ID:2316
Ensembl ID:ENSG00000196924

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CARDIAC VALVULAR DYSPLASIA, X-LINKED 
FG SYNDROME 2 
FRONTOMETAPHYSEAL DYSPLASIA 
HETEROTOPIA, PERIVENTRICULAR 
HETEROTOPIA, PERIVENTRICULAR, ED VARIANT 
INTESTINAL PSEUDOOBSTRUCTION, NEURONAL 
MELNICK-NEEDLES SYNDROME 
OTOPALATODIGITAL SYNDROME, TYPE II 
OTOPALATODIGITAL SYNDROME,TYPE I 
TERMINAL OSSEOUS DYSPLASIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq28Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 153576898 - 153599585

 Exon Info From UCSC:
NM_001110556
NM_001456

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4152096IncompleteBC041179filamin A, alpha (actin binding protein 280)
4800733IncompleteBC067111filamin A, alpha (actin binding protein 280)
40034073IncompleteBC109289filamin A, alpha (actin binding protein 280)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001447  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001110556 NP_001104026 P21333  
NM_001456 NP_001447 P21333 CH
Filamin

Related Sequences

 
mRNAGenPeptSwissProt
BC014654 AAH14654 Q96C61
BC041179 AAH41179 Q86TQ3
BC067111 AAH67111 Q6NXF2
BC109289 AAI09290 Q2VP91
GU727643 ADU87644 P21333
AK074048 BAB84874 Q8TES4
AK090427 BAC03408 P21333
AB191259 BAD52435 Q60FE6
AB191260 BAD52436 Q60FE5
AB371574 BAG48303 Q60FE5
AB371575 BAG48304 Q60FE6
AB371576 BAG48305 Q60FE5
AB371577 BAG48306 A6NDY9
AB371578 BAG48307 Q60FE6
AB371579 BAG48308 Q60FE6
AK300165 BAG61947 B4DTD5
AK304255 BAG65121 B4E2F9
AB593010 BAJ83965 P21333
X53416 CAA37495 P21333

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FLNA NP_001104026 M.musculus Flna 192176 Gene Info NP_034357 97
R.norvegicus Flna 293860   NP_001128071 97
A.gambiae AgaP_AGAP004335 1274482   XP_313613 44
C.elegans Y66H1B.2 176855   NP_001033457 43
D.melanogaster cher 42066   NP_996224 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)