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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HSD11B1, hydroxysteroid (11-beta) dehydrogenase 1
Sequence ID:NM_001206741
NM_005525
NM_181755
RefSeqGene ID:NG_012081
Entrez Gene ID:3290
Ensembl ID:ENSG00000117594

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CORTISONE REDUCTASE DEFICIENCY 1H6PD
CORTISONE REDUCTASE DEFICIENCY 2 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q32-q41Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 209878193 - 209907866

 Exon Info From UCSC:
NM_005525
NM_181755

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4286028Full LengthBC012593hydroxysteroid (11-beta) dehydrogenase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_861420  NP_005516  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001206741 NP_001193670      
NM_005525 NP_005516 P28845 EC 1.1.1.146 adh_short
NM_181755 NP_861420 P28845 EC 1.1.1.146 adh_short

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC012593 AAH12593 P28845 EC 1.1.1.146
DQ892912 ABM83838    
EU176721 ABW03522    
AK313973 BAG36688 P28845 EC 1.1.1.146

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HSD11B1 NP_001193670 M.musculus Hsd11b1 15483 Gene Info NP_001038216 79
R.norvegicus Hsd11b1 25116   NP_058776 77
A.thaliana HSD7 835140   NP_680417 34
A.thaliana HSD4 835128   NP_199871 34
A.thaliana HSD2 823889   NP_190319 33
A.thaliana HSD3 823890   NP_190320 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta