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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EZH1, enhancer of zeste homolog 1 (Drosophila)
Sequence ID:NM_001991
Entrez Gene ID:2145
Ensembl ID:ENSG00000108799

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21.1-q21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 40852287 - 40882934

 Exon Info From UCSC:
NM_001991

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3908776Full LengthBC015882enhancer of zeste homolog 1 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001982  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001991 NP_001982 Q92800 EC 2.1.1.43 SET

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L38934 AAB59574 Q92800 EC 2.1.1.43
U50315 AAC50778 Q92800 EC 2.1.1.43
BC015882 AAH15882 Q92800 EC 2.1.1.43
BT009782 AAP88784 Q92800 EC 2.1.1.43
AB002386 BAA20842 Q92800 EC 2.1.1.43
AB004818 BAA25019 Q92800 EC 2.1.1.43
AK295626 BAG58503 Q92800 EC 2.1.1.43
AK295853 BAG58659 Q92800 EC 2.1.1.43
AK299887 BAG61734 Q92800 EC 2.1.1.43
AK304835 BAG65579 Q92800 EC 2.1.1.43

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EZH1 NP_001982 M.musculus Ezh1 14055 Gene Info NP_031996 98
R.norvegicus Ezh1 303547   NP_001100521 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta