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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. LEP, leptin
Sequence ID:NM_000230
RefSeqGene ID:NG_007450
Entrez Gene ID:3952
Ensembl ID:ENSG00000174697

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q31.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 127892054 - 127894934

NM_000230 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262097Full LengthBC069323leptin
7262109Full LengthBC069452leptin
7262121Full LengthBC069527leptin
30333193Full LengthBC060830leptin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000221  

Protein Infomation

NM_000230 NP_000221 P41159 Leptin

Related Sequences

U18915 AAA60470 P41159
AF008123 AAB63507 P41159
U43653 AAC50400 P41159
BC060830 AAH60830 P41159
BC069323 AAH69323 Q6NT58
BC069452 AAH69452 P41159
BC069527 AAH69527 P41159
HQ448411 ADQ32891  
D49487 BAA08448 P41159
AK313553 BAG36329 B2R8Y2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens LEP NP_000221 M.musculus Lep 16846 Gene Info NP_032519 83
R.norvegicus Lep 25608   NP_037208 82

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta