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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AGT, angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Sequence ID:NM_000029
RefSeqGene ID:NG_008836
Entrez Gene ID:183
Ensembl ID:ENSG00000135744

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPERTENSIONADD1
AGTR1
AGTR1
ATP1B1
ATP1B1
CYP3A5
ECE1
GNB3
NOS2
NOS3
PTGIS
RGS5
RGS5
SELE
RENAL TUBULAR DYSGENESISACE
AGTR1
AGTR1
REN

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q42.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 230838475 - 230849848

NM_000029 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
9810230838273230839074
811955230839938230840082
9561223230841678230841945
12242082230845740230846598
20832587230849831230850335

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4213559Full LengthBC011519angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000020  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000029 NP_000020 P01019 Serpin

Related Sequences

 
mRNAGenPeptSwissProt
K02215 AAA51731 P01019
M69110 AAA52282 P01019
BC011519 AAH11519 Q86U78
P01019
BT006851 AAP35497 Q86U78
DQ891016 ABM81942  
DQ894196 ABM85122  
AB209769 BAD93006 Q59EP2
AK222798 BAD96518 Q53GY3
AK222815 BAD96535 Q53YY1
AK312291 BAG35218 B2R5S1
AK293507 BAG56991 B4DE80
AK303755 BAG64725 B4E1B3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AGT NP_000020 R.norvegicus Agt 24179   NP_602308 64
M.musculus Agt 11606 Gene Info NP_031454 61

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta