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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. IL10, interleukin 10
Sequence ID:NM_000572
RefSeqGene ID:NG_012088
Entrez Gene ID:3586
Ensembl ID:ENSG00000136634

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AIDS, RAPID PROGRESSION TOCCL11
CCL2
CCL3
CCL3L1
CD209
CX3CR1
CXCL12
CXCR1
HLA-C
HLA-C
HLA-C
IFNG
IL4R
IL4R
KIR3DL1
GRAFT-VERSUS-HOST DISEASE,PROTECTION AGAINST 
RHEUMATOID ARTHRITISCD244
CIITA
HLA-DRB1
HLA-DRB1
HLA-DRB1
NFKBIL1
PADI4
PTPN22
RUNX1
RUNX1
SLC22A4
STAT4
STAT4

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q31-q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 206941947 - 206945726

NM_000572 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11126206940947206942072
11271192206943173206943238
11931345206944251206944403
13461405206944700206944759
14061629206945615206945838

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40035920Full LengthBC104252interleukin 10
40035922Full LengthBC104253interleukin 10

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000563  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000572 NP_000563 Q6FGW4
P22301
IL10

Related Sequences

 
mRNAGenPeptSwissProt
M57627 AAA63207 Q6FGW4
P22301
AF043333 AAC03534 Q71UZ1
BC104252 AAI04253 Q6FGW4
P22301
BC104253 AAI04254 Q6FGW4
P22301
AY029171 AAK38162 Q6FGW4
P22301
CR541993 CAG46790 Q6FGW4
P22301
CR542028 CAG46825 Q6FGS9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IL10 NP_000563 R.norvegicus Il10 25325   NP_036986 74
M.musculus Il10 16153 Gene Info NP_034678 73

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta