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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MTAP, Methylthioadenosine phosphorylase
Sequence ID:NM_002451
RefSeqGene ID:NG_032650
Entrez Gene ID:4507
Ensembl ID:ENSG00000099810

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DIAPHYSEAL MEDULLARY STENOSIS WITH MALIGNANT FIBROUS HISTIOCYTOMA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:9p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 21862320 - 21863623

NM_002451 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11462180263421802779
1472332181543121815517
2342922181671221816770
2934602181803321818200
4615632183790621838008
5648032185462921854868
8049262185930121859423
92749192186197421865966

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3030148Full LengthBC018625methylthioadenosine phosphorylase
3546198Full LengthBC012316methylthioadenosine phosphorylase
4820938Full LengthBC026106methylthioadenosine phosphorylase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002442  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002451 NP_002442 Q13126 EC 2.4.2.28 Mtap_PNP

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U22233 AAA81646 Q13126 EC 2.4.2.28
AF109294 AAD19641    
AF216650 AAF82688 Q9NRK7  
L40432 AAG38871 Q13126 EC 2.4.2.28
BC012316 AAH12316 Q05DJ2  
BC018625 AAH18625 Q8WV80  
BC026106 AAH26106 Q13126 EC 2.4.2.28
AY712791 AAU04442 Q13126 EC 2.4.2.28
JF432462 ADZ15679    
AB062485 BAB93510 Q8NI75  
AK300592 BAG62290 B4DUC8  
CR541670 CAG46471 Q6FHT1  
CR541710 CAG46511 Q6FHP1  
HE654772 CCF77345 Q13126 EC 2.4.2.28
HE654773 CCF77346 Q13126 EC 2.4.2.28
HE654774 CCF77347 Q13126 EC 2.4.2.28
HE654775 CCF77348 Q13126 EC 2.4.2.28
HE654776 CCF77349 Q13126 EC 2.4.2.28
HE654777 CCF77350 Q13126 EC 2.4.2.28

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MTAP NP_002442 M.musculus Mtap 66902 Gene Info NP_077753 94
A.gambiae AgaP_AGAP005129 1274807   XP_314011 66
D.melanogaster CG4802 36955   NP_611208 62
C.elegans B0228.7 174252   NP_495629 51
N.crassa NCU03963 3873724   XP_957602 44
S.pombe SPAC16C9.02c 2542316   NP_593076 40
S.cerevisiae MEU1 850704   NP_013117 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)